Mańkowski W, Klimaszyk D, Krupiński B
Oddział Chorób Zawodowych i Toksykologii im. dr Wandy Błeńskiej, Wielkopolskiego Centrum Medycyny Pracy w Poznaniu.
Przegl Lek. 2000;57(10):588-90.
18-year-old man was found at the street in an unconsious state and brought to Department of Acute Poisonings with suspicion of unknown xenobiotic ingestion. There was no reliable informations concerning poisoning circumstances. On admission patient was confused and unable to answer questions; physical examination revealed symptoms resembling ethanol intoxication. Results of laboratory tests (e.g., ketonemia and lack of abnormalities of gasometric parameters; ethanol, methanol and ethylene glycol in blood and urine were absent) enabled to presume acute poisoning with isopropyl alcohol. According to informations obtained from patient's parents he had drunk unknown amount of liquid using as printing machine cleaner. During next hours rising acetone concentration in blood (1.7 g/l--4 hours after admission, 2.4 g/l--12 hours after admission) and ketonuria were observed. There was no possibility to evaluate level of isopropanol in blood and urine up to 12 hours after admission--gas chromatography performed at that time revealed lack of isopropanol both in blood and urine. Liquid brought by patient's parents was identified (on gas chromatography) as isopropyl alcohol. Patient was directed to be treated on hemodialysis, because of high concentration acetone in blood. After 16 hours--long hemodialysis patient came back to Department of Acute Poisonings. 3 days later patient left hospital in good condition.
一名18岁男性被发现昏迷在街头，被送往急性中毒科，怀疑摄入了不明外源性物质。关于中毒情况没有可靠信息。入院时患者神志不清，无法回答问题；体格检查发现有类似乙醇中毒的症状。实验室检查结果（如酮血症和气体测量参数无异常；血液和尿液中未检测到乙醇、甲醇和乙二醇）提示可能是异丙醇急性中毒。根据从患者父母处获得的信息，他饮用了未知量用作印刷机清洁剂的液体。在接下来的几个小时里，观察到血液中丙酮浓度升高（入院后4小时为1.7g/L，入院后12小时为2.4g/L）以及酮尿。入院后12小时内无法评估血液和尿液中的异丙醇水平——当时进行的气相色谱分析显示血液和尿液中均无异丙醇。患者父母带来的液体经气相色谱鉴定为异丙醇。由于血液中丙酮浓度高，患者被安排进行血液透析治疗。经过16小时的血液透析后，患者回到急性中毒科。3天后患者康复出院。
