Cho B R
Avian Dis. 1975 Jan-Mar;19(1):67-74.
The development and persistence of viremia were followed in two lines of Single-Comb White Leghorns: one experimental line (WSU-VS) highly susceptible, and one commercial line (C-WL) relatively resistant to Marek's disease(MD). In the resistant C-WL chicken, viremia with a mild strain of MD herpesvirus (MDHV) persisted in all viremic birds through 8 weeks postinoculation (PI), while viremia with an acute strain of MDHV did not, resulting in a decrease in number of viremic birds after 2 weeks PI. In the susceptible WSU-VS chicken, viremia with acute MDHV persisted in all viremic birds whereas viremia with mild MDHV was detected in a decreasing number of birds after 6 weeks PI. The pattern of viremia observed in the dually infected groups simulated a combination of the responses of the two groups respectively inoculated with mild and acute MDHV. Whether inoculation was with acute MDHV alone, or together with mild MDHV, levels of viremia with acute MDHV were appreciably higher in the WSU-VS than in the C-WL chicken. In both lines, levels of viremia were higher with acute MDHV than with mild MDHV but viremia with acute MDHV could not be demonstrated in the C-WL bird at 6-8 weeks PI. Levels of viremia with mild MDHV were consistently and similarly low in both WSU-VS and C-WL chickens.
一个是对马立克氏病（MD）高度易感的实验品系（WSU-VS），另一个是相对抗性的商业品系（C-WL）。在抗性C-WL鸡中，感染温和型马立克氏病疱疹病毒（MDHV）毒株的病毒血症在所有病毒血症鸡中持续到接种后8周，而感染急性MDHV毒株的病毒血症则不然，导致接种后2周病毒血症鸡的数量减少。在易感的WSU-VS鸡中，感染急性MDHV的病毒血症在所有病毒血症鸡中持续存在，而感染温和型MDHV的病毒血症在接种后6周在越来越少的鸡中被检测到。在双重感染组中观察到的病毒血症模式分别模拟了两组分别接种温和型和急性MDHV后的反应组合。无论是单独接种急性MDHV，还是与温和型MDHV一起接种，WSU-VS鸡中急性MDHV的病毒血症水平明显高于C-WL鸡。在两个品系中，急性MDHV的病毒血症水平都高于温和型MDHV，但在接种后6至8周，C-WL鸡中未检测到急性MDHV的病毒血症。WSU-VS和C-WL鸡中温和型MDHV的病毒血症水平一直且相似地较低。
