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本文引用的文献

1
Prevalence of diabetes in Catalonia (Spain): an oral glucose tolerance test-based population study.西班牙加泰罗尼亚地区糖尿病患病率：一项基于口服葡萄糖耐量试验的人群研究。
Diabetes Res Clin Pract. 1999 Jan;43(1):33-40. doi: 10.1016/s0168-8227(98)00125-9.
2
Diabetes and lower-limb amputations in the community. A retrospective cohort study. DARTS/MEMO Collaboration. Diabetes Audit and Research in Tayside Scotland/Medicines Monitoring Unit.社区中的糖尿病与下肢截肢。一项回顾性队列研究。DARTS/MEMO协作组。苏格兰泰赛德糖尿病审计与研究/药物监测单位。
Diabetes Care. 1998 May;21(5):738-43. doi: 10.2337/diacare.21.5.738.
3
Nontraumatic lower extremity amputations in diabetic and non-diabetic subjects in Madrid, Spain.西班牙马德里糖尿病和非糖尿病患者的非创伤性下肢截肢情况。
Diabetes Metab. 1997 Dec;23(6):519-23.
4
The impact of diabetes-related lower-extremity amputations in The Netherlands.荷兰糖尿病相关下肢截肢的影响。
J Diabetes Complications. 1996 Nov-Dec;10(6):325-30. doi: 10.1016/1056-8727(95)00088-7.
5
Incidence of lower limb amputations and diabetes.下肢截肢与糖尿病的发病率。
Diabetes Care. 1996 Sep;19(9):1006-9. doi: 10.2337/diacare.19.9.1006.
6
Diabetes and nontraumatic lower extremity amputations. Incidence, risk factors, and prevention--a 12-year follow-up study in Nauru.糖尿病与非创伤性下肢截肢。发病率、危险因素及预防——瑙鲁的一项12年随访研究
Diabetes Care. 1996 Jul;19(7):710-4. doi: 10.2337/diacare.19.7.710.
7
Long-term incidence of lower-extremity amputations in a diabetic population.糖尿病患者下肢截肢的长期发生率。
Arch Fam Med. 1996 Jul-Aug;5(7):391-8. doi: 10.1001/archfami.5.7.391.
8
Decreasing incidence of major amputation in diabetic patients: a consequence of a multidisciplinary foot care team approach?糖尿病患者大截肢发生率的降低：多学科足部护理团队方法的结果？
Diabet Med. 1995 Sep;12(9):770-6. doi: 10.1111/j.1464-5491.1995.tb02078.x.
9
Reduction of lower extremity clinical abnormalities in patients with non-insulin-dependent diabetes mellitus. A randomized, controlled trial.
Ann Intern Med. 1993 Jul 1;119(1):36-41. doi: 10.7326/0003-4819-119-1-199307010-00006.
10
Lower-extremity amputation. Incidence, risk factors, and mortality in the Oklahoma Indian Diabetes Study.
Diabetes. 1993 Jun;42(6):876-82. doi: 10.2337/diab.42.6.876.

[马拉加糖尿病患者人群下肢截肢的发生率（1996 - 1997年）]

[Incidence of amputaciones of the lower extremities in the population with diabetes mellitus in Málaga (1996-1997)].

作者信息

Almaraz M C, Soriguer F, Zamorano D, Ruiz de Adana S, González E, Esteva I, García J, López M J

机构信息

Unidad de Atención al Pie Diabético, Servicio de Endocrinología y Nutrición, Hospital Civil, Complejo Hospitalario Carlos Haya.

出版信息

Aten Primaria. 2000 Dec;26(10):677-80. doi: 10.1016/s0212-6567(00)78750-6.

DOI:10.1016/s0212-6567(00)78750-6
PMID:11200511
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7681367/
Abstract

OBJECTIVE

To find the frequency of amputations of lower limbs (ALL) with the aim of designing a programme to prevent ALL in people with diabetes mellitus (DM).

DESIGN

Retrospective observation study.

SETTING

Population study in Malaga and its province.

PATIENTS

The clinical records of everyone with ALL in public or subsidized hospitals in the province of Malaga between January 1 1996 and December 31 1997 were reviewed. Traumatic or tumoural ALL were excluded. Cumulative incidence, relative risk (RR) of ALL and the mortality rate of people with DM were calculated.

RESULTS

449 ALL took place during the period studied, 316 (70.3%) in people with DM and 133 (29.6%) in people not suffering DM. The incidence of ALL per 100,000 people and per year was 6.3 (CI: 4.7-7.8) in the population without DM and 136.1 (CI: 114.9-157.3) in people with DM. The RR of ALL was 21.6 (CI: 17.6-26.4) for the population with DM, with differences between men and women (16.8 vs. 36.1, respectively). Mean age of ALL was significantly greater (p < 0.05) for the population with DM (70.0 +/- 10.2 vs. 68.9 +/- 15.9 years old). Older ALL were more numerous in both women and men in the two groups studied. The mortality rate, complications and mean stay in hospital were greater in the population with DM.

CONCLUSIONS

This study confirmed the greater risk of ALL run by people with DM. The incidence of ALL in this study was less than in countries of Northern Europe, the USA and Australia, but more than in any study published before in Spain.

摘要

目的

为设计一项预防糖尿病患者下肢截肢（ALL）的方案，找出下肢截肢的发生率。

设计

回顾性观察研究。

背景

在马拉加及其省份开展的人群研究。

患者

对1996年1月1日至1997年12月31日期间马拉加省公立或补贴医院中所有下肢截肢患者的临床记录进行了回顾。排除创伤性或肿瘤性下肢截肢病例。计算了下肢截肢的累积发病率、相对风险（RR）以及糖尿病患者的死亡率。

结果

在研究期间共发生449例下肢截肢，其中糖尿病患者316例（70.3%），非糖尿病患者133例（29.6%）。非糖尿病人群中每10万人每年的下肢截肢发病率为6.3（可信区间：4.7 - 7.8），糖尿病患者中为136.1（可信区间：114.9 - 157.3）。糖尿病患者下肢截肢的相对风险为21.6（可信区间：17.6 - 26.4），男性和女性之间存在差异（分别为16.8和36.1）。糖尿病患者下肢截肢的平均年龄显著更高（p < 0.05）（70.0 ± 10.2岁 vs. 68.9 ± 15.9岁）。在两个研究组中，年龄较大的下肢截肢患者在男性和女性中都更多。糖尿病患者的死亡率、并发症发生率和平均住院时间更高。

结论

本研究证实糖尿病患者发生下肢截肢的风险更高。本研究中下肢截肢的发生率低于北欧国家、美国和澳大利亚，但高于此前西班牙发表的任何研究。