Willows N D, Dewailly E, Gray-Donald K
School of Dietetics and Human Nutrition, McGill University, Macdonald Campus, Ste. Anne de Bellevue, Quebec.
Can J Public Health. 2000 Nov-Dec;91(6):407-10. doi: 10.1007/BF03404818.
The iron status and diet of Inuit infants living in northern Quebec who were part of a prospective cohort study was described. The prevalence of anemia (hemoglobin values > 2 SD below the reference mean) was 21.1% (23/109), 47.4% (55/116) and 37.7% (46/122) at 2, 6 and 12 months, respectively. The corresponding prevalence of microcytic anemia was 0.0%, 4.3% and 21.3%. At 2, 6 and 12 months, iron-deficiency anemia (serum ferritin < 10 micrograms/L coupled with anemia) was present in 1.3% (1/79), 24.4% (21/86) and 26.3% (25/95) of infants, respectively. Compared with breastfeeding, the odds ratio for iron deficiency (serum ferritin < 10 micrograms/L) for bottle-feeding with cows' milk or low iron formula was 3.02 (95% CI 1.25-7.27) at 6 months and 3.05 (95% CI 1.28-7.28) at 12 months. This study shows iron-deficiency anemia to be a problem in Inuit infants as young as 6 months old. Breastfed infants were better protected against iron deficiency than infants fed cow's milk or low-iron formula.
描述了居住在魁北克北部、参与一项前瞻性队列研究的因纽特婴儿的铁状态和饮食情况。贫血（血红蛋白值低于参考均值2个标准差以上）的患病率在2个月、6个月和12个月时分别为21.1%（23/109）、47.4%（55/116）和37.7%（46/122）。小细胞性贫血的相应患病率分别为0.0%、4.3%和21.3%。在2个月、6个月和12个月时，缺铁性贫血（血清铁蛋白<10微克/升并伴有贫血）分别在1.3%（1/79）、24.4%（21/86）和26.3%（25/95）的婴儿中出现。与母乳喂养相比，6个月时用牛奶或低铁配方奶粉人工喂养的缺铁（血清铁蛋白<10微克/升）比值比为3.02（95%置信区间1.25 - 7.27），12个月时为3.05（95%置信区间1.28 - 7.28）。这项研究表明，缺铁性贫血在6个月大的因纽特婴儿中是一个问题。母乳喂养的婴儿比用牛奶或低铁配方奶粉喂养的婴儿更能有效预防缺铁。
