Tani T, Okada K, Shoji K, Hashimoto M, Sageshima M
Department of Orthopaedics, Akita University School of Medicine, Japan.
Skeletal Radiol. 2000 Nov;29(11):656-9. doi: 10.1007/s002560000271.
We report an osteoblastoma-like osteosarcoma in the right proximal fibula in a 22-year-old woman. Radiographs showed an irregular osteolytic lesion from the metaphysis to the epiphysis in the proximal fibula with partial destruction of cortical bone. Tissue from a biopsy indicated a typical osteoblastoma. Curettage and bone graft was performed. One year after the surgery, local recurrence occurred, and a wide excision was performed. Histological examination of the en-bloc surgical specimen revealed the tumor had permeated through the host bony trabeculae, although the nuclear atypia was not marked. Immunohistochemical expression of MIB-1 was detected in 9.0% of cells.
我们报告了一名22岁女性右腓骨近端的骨母细胞瘤样骨肉瘤。X线片显示右腓骨近端从干骺端到骨骺的不规则溶骨性病变，皮质骨部分破坏。活检组织显示为典型的骨母细胞瘤。进行了刮除术和骨移植。术后一年出现局部复发，遂行广泛切除术。整块手术标本的组织学检查显示肿瘤已穿透宿主骨小梁，尽管核异型性不明显。MIB-1的免疫组化表达在9.0%的细胞中被检测到。
