Lezhnin V L, Polzik E V, Kazantsev V S, Mashintsov E A, Simonov A F
Institute of Industrial Environmental Studies, Russian Academy of Sciences, Urals Branch, Yekaterinburg.
Vopr Onkol. 2000;46(5):555-60.
A multifactorial epidemiologic study of high incidence of lung cancer was conducted in the city of Tula. Mathematical methods of pattern recognition were used. The influence of 20 factors of risk was evaluated. The leading ones were tobacco smoking, occupational exposure to carcinogenic substances and precancerous lesions in the lungs. The influence of industrial pollution on cancer morbidity was assessed as moderate. Mathematical estimates for effectiveness of correction of "controllable" risk factors were given.
在图拉市开展了一项关于肺癌高发病率的多因素流行病学研究。采用了模式识别的数学方法。评估了20种风险因素的影响。其中主要因素为吸烟、职业性接触致癌物质以及肺部的癌前病变。工业污染对癌症发病率的影响被评估为中等。给出了校正“可控”风险因素有效性的数学估计。