非培养方法在机会性和地方性真菌病诊断与管理中的临床应用

Clinical applications of non-culture based methods for the diagnosis and management of opportunistic and endemic mycoses.

作者信息

Verweij P E, Figueroa J, Van Burik J, Holdom M D, Dei-Cas E, Gómez B L, Mendes-Giannini M J

机构信息

Department of Medical Microbiology, University Medical Center Nijmegen, The Netherlands.

出版信息

Med Mycol. 2000;38 Suppl 1:161-71.

PMID:11204141

Abstract

Nonculture based methods for the detection of infections caused by fungal pathogens are becoming more important tools in the management of infected patients. Detection of fungal antigens and DNA appear to be the most promising in this respect for both opportunistic and endemic mycoses. In this article we present an overview of the most recent developments in nonculture based methods and examine their value in clinical practice.

摘要

基于非培养的方法检测真菌病原体引起的感染，正成为感染患者管理中越来越重要的工具。在这方面，检测真菌抗原和DNA对于机会性真菌病和地方性真菌病似乎最具前景。在本文中，我们概述了基于非培养方法的最新进展，并探讨了它们在临床实践中的价值。