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伪狂犬病病毒(又称奥耶斯基氏病病毒)疫情的数学建模有助于根除计划:综述

Mathematical modelling of pseudorabies virus (syn. Aujeszky's disease virus) outbreaks aids eradication programmes: a review.

作者信息

van Nes A

机构信息

Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.

出版信息

Vet Q. 2001 Jan;23(1):21-6. doi: 10.1080/01652176.2001.9695070.

Abstract

Pseudorabies virus will be eradicated from the Netherlands if a typical infectious pig (Rind) infects, on average, less than one other pig. In this review, we used a stochastic SIR model to estimate Rind using data from the field and from experiments. Rind in sow herds was estimated to be significantly less than 1 and in rearing and finishing pigs Rind was higher than 1. However, if Rind is higher than 1, PRV can still be eradicated if one infectious herd infects less than one other herd during the period that the herd is infectious(Rherd <1). Some future developments in Dutch pig husbandry (e.g. group-housing of sows) and possible risks after halting vaccination are also quantitatively evaluated.

摘要

如果一头典型的感染猪平均感染的其他猪只少于一头,伪狂犬病病毒将在荷兰被根除。在本综述中,我们使用了一个随机SIR模型,利用来自现场和实验的数据来估计感染率(Rind)。估计母猪群中的感染率显著低于1,而在育肥猪群中感染率高于1。然而,如果感染率高于1,在感染猪群具有传染性的期间,如果一个感染猪群感染的其他猪群少于一个(群体感染率Rherd <1),伪狂犬病病毒仍然可以被根除。我们还对荷兰养猪业未来的一些发展(例如母猪的群体饲养)以及停止疫苗接种后可能存在的风险进行了定量评估。

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