Kaudewitz P, Klövekorn W, Rother W
Department of Dermatology, Ludwig-Maximilians-University Munich, Munich, Germany.
Dermatol Surg. 2001 Feb;27(2):101-6. doi: 10.1046/j.1524-4725.2001.00266.x.
A variety of lasers have been used in an attempt to treat leg vein telangiectasia
To evaluate the feasibility of a new 940 nm diode laser for the treatment of leg vein telangiectasia.
Thirty-one patients with leg vein telangiectasia were treated with a diode laser; 26 of these with 940 nm, 300-350 J/cm2, 40-70 msec, 1.0 mm handpiece, one pass, and 5 of these with 940 nm, 815 J/cm2, 50 msec, 0.5 mm handpiece, one pass. Each subject had three treatments of the same site at 4-week intervals. Photographs taken before and 4 weeks after the last treatment were evaluated by two independent observers for vessel clearance.
In those 26 patients treated with a fluence of 300-350 J/cm2, a vessel clearance of greater than 50% was achieved in 20 patients (76%), 12 of these patients had clearance rates greater than 75%. A clearance rate of less than 50% was obtained in six patients, with three of these patients showing responses of less than 25%. In five patients treated with a fluence of 815 J/cm2 a clearance rate of more than 75% was observed.
In this preliminary study a 940 nm diode laser was shown to be safe and effective for the treatment of leg vein telangiectasia.
为治疗腿部静脉扩张，人们尝试使用了多种激光。
评估新型940纳米二极管激光治疗腿部静脉扩张的可行性。
31例腿部静脉扩张患者接受了二极管激光治疗；其中26例采用940纳米、300 - 350 J/cm²、40 - 70毫秒、1.0毫米手持探头、单次照射，5例采用940纳米、815 J/cm²、50毫秒、0.5毫米手持探头、单次照射。每位受试者在同一部位每隔4周接受三次治疗。由两名独立观察者对最后一次治疗前及治疗后4周拍摄的照片进行血管清除情况评估。
在26例接受300 - 350 J/cm²能量密度治疗的患者中，20例（76%）血管清除率大于50%，其中12例患者清除率大于75%。6例患者清除率小于50%，其中3例患者反应率小于25%。在5例接受815 J/cm²能量密度治疗的患者中，观察到清除率超过75%。
在这项初步研究中，940纳米二极管激光被证明对治疗腿部静脉扩张安全有效。
