膜泡运输中的马达蛋白、离合器和制动器：纪念托马斯·克雷斯的综述

Motors, clutches and brakes for membrane traffic: a commemorative review in honor of Thomas Kreis.

作者信息

Schroer T A

机构信息

Department of Biology, Johns Hopkins University, Department of Biology, 34th and Charles Sts., Baltimore, MD 21218, USA.

出版信息

Traffic. 2000 Jan;1(1):3-10. doi: 10.1034/j.1600-0854.2000.010102.x.

DOI:10.1034/j.1600-0854.2000.010102.x

PMID:11208053

Abstract

Membranous organelles interact with a wide variety of cytoskeletal proteins that allow them to be organized into dynamic, yet stable, structures with distinct subcellular addresses. This review provides an up-to-date summary of the motor enzymes and membrane-microtubule crosslinking proteins that have been implicated in this process, and discusses the potential impact membrane anchoring may have on cellular architecture.

摘要

膜性细胞器与多种细胞骨架蛋白相互作用，这些蛋白使它们能够被组织成具有不同亚细胞定位的动态但稳定的结构。本综述提供了参与这一过程的运动酶和膜 - 微管交联蛋白的最新总结，并讨论了膜锚定对细胞结构可能产生的潜在影响。