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非常规肌球蛋白:膜转运中继中的锚定蛋白

Unconventional myosins: anchors in the membrane traffic relay.

作者信息

Tuxworth R I, Titus M A

机构信息

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.

出版信息

Traffic. 2000 Jan;1(1):11-8. doi: 10.1034/j.1600-0854.2000.010103.x.

Abstract

The family of unconventional myosins is ever growing and the functions attributed to them seem to expand in parallel. These actin-based motor proteins have been implicated in processes as seemingly diverse as endocytosis and exocytosis, the transport of organelles, in spermatogenesis and in neurosensory functions such as hearing and sight. A common myosin function may underlie them all--the regulation of intracellular membrane traffic.

摘要

非常规肌球蛋白家族不断壮大,与之相关的功能似乎也在同步扩展。这些基于肌动蛋白的运动蛋白参与了许多看似不同的过程,如胞吞作用和胞吐作用、细胞器运输、精子发生以及听觉和视觉等神经感觉功能。它们可能都有一个共同的肌球蛋白功能——调节细胞内膜运输。

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