Gharoro E P, Igbafe A A
Departement of Obstetrics and Gynecology, University of Benin Teaching Hospital, Benin City, Nigeria.
Med Sci Monit. 2000 Jan-Feb;6(1):84-7.
Drugs taken by pregnant women could have profound effect on pregnancy outcome for both the mother and fetus. In most developing country regulation of drug is poor, access is unrestricted and abuse of drugs especially antibiotics is rampant. The study was undertaken to determine the pattern and extent of drug consumption amongst pregnant women in Benin City.
A cross-sectional study of 1200 pregnant patients at various gestational ages was undertaken, using a structured questionnaire to obtain details of the extent and character of drug use before or during pregnancy.
Folic acid was taken by 76.08% of all the pregnant patients, while anti-malarial drugs were taken by 19.75%; 15.83% used the drugs on doctors' prescription and 3.92% without a doctor's prescription. The proportion of the mothers that consumed native herbs was 12.08%. The use of native medication was more prevalent amongst nulliparous mothers (41.82%). Native herb consumption decreased with increase in parity. Both educated and illiterate mothers consumed herbal medications. Less than 1% of the mothers smoke cigarettes.
In Benin City drug use in pregnancy is characterized by a pattern of low consumption except folic acid and native herbs. This could be a major setback for any program of drug intervention, as in chemoprophylaxis for malaria in pregnancy. Much resource will be needed for patients' education for successful implementation of any planned program in the community.
孕妇服用的药物可能对母亲和胎儿的妊娠结局产生深远影响。在大多数发展中国家，药物监管不力，获取不受限制，药物滥用尤其是抗生素滥用猖獗。本研究旨在确定贝宁城孕妇的药物消费模式和程度。
对1200名不同孕周的孕妇进行横断面研究，使用结构化问卷获取妊娠前或妊娠期间用药程度和特征的详细信息。
所有孕妇中76.08%服用叶酸，19.75%服用抗疟药物；15.83%按医生处方用药，3.92%无医生处方用药。服用天然草药的母亲比例为12.08%。天然药物的使用在初产妇中更为普遍（41.82%）。随着产次增加，天然草药的消费减少。受过教育和未受过教育的母亲都使用草药。不到1%的母亲吸烟。
在贝宁城，除叶酸和天然草药外，孕期用药呈现低消费模式。这可能是任何药物干预项目（如孕期疟疾化学预防）的重大挫折。为在社区成功实施任何计划项目，需要大量资源用于患者教育。
