Maciejewski A, Lange D, Włoch J
Department Oncological Surgery, Oncology Center, M. Skłodowska-Curie Memorial Institute, Gliwice, Poland.
Med Sci Monit. 2000 Jul-Aug;6(4):779-82.
The case of benign schwannoma of the rectum primarily misdiagnosed as myogenic (neurogenic?) sarcoma is presented. A large tumor of 8 cm in diameter of the anterior rectal wall was removed with wide margins and an artificial anus was constructed. During 12 years of follow-up neither local recurrence nor distant metastases were observed. The patient is still alive and free of the disease. For that reason a surgery specimen of the tumor was pathologically reanalyzed and it showed features of type Antoni A and B tissues. These findings, together with strong reactivity for S-100 protein, Vimentin and negative for Actin supported the diagnosis of benign schwannoma. Because the localization of the tumor in the rectum is extremely rare, clinical and pathological features are presented and discussed.
本文报告一例最初被误诊为肌源性（神经源性？）肉瘤的直肠良性神经鞘瘤病例。患者直肠前壁有一个直径8厘米的大肿瘤，已行广泛切除并造人工肛门。随访12年，未观察到局部复发或远处转移。患者仍存活且无疾病。因此，对肿瘤手术标本进行了病理重新分析，显示出Antoni A型和B型组织特征。这些发现，连同对S-100蛋白、波形蛋白呈强反应性以及对肌动蛋白呈阴性，支持了良性神经鞘瘤的诊断。由于肿瘤位于直肠极为罕见，故介绍并讨论了其临床和病理特征。
