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计划手术中肾癌患者保留器官手术结果的评估。

Evaluation of organ sparing surgery results in patients with kidney cancer in scheduled operations.

作者信息

Fryczkowski M, Potyka A, Huk J

机构信息

Department of Urology, Silesian Medical University, ul. 3 Maja 13/15, 41-800 Zabrze, Poland.

出版信息

Med Sci Monit. 2000 Nov-Dec;6(6):1098-103.

Abstract

INTRODUCTION

The aim of the study was retrospective analysis of nephron-sparing surgery results of 53 patients, performed due to unilateral small kidney tumors in the period of 1988-1998.

MATERIAL AND METHODS

The patients were followed-up according to EORTC directions for 20 to 143 months after the surgery. We have treated 25 women and 28 men of the average age of 53.7. In ten patients partial nephrectomy was performed and the remaining 43 had the tumor enucleated.

RESULTS

The average observation time without any recurrences and metastases was 63.8 months, in 5.7% of patients local disease related recurrences and in 1.9% remote recurrences have been found.

CONCLUSIONS

  1. Nephron-sparing surgery is a safe alternative to radical surgery in tumors of up to 4 cm in diameter. 2. Prospective 10-year survival time in our patients was 98%, including 92% of patients remaining without recurrence or metastases. 3. Positive prognostic factors are incidental diagnosis of a tumor and low staging and grading of a tumor.
摘要

引言

本研究的目的是对1988年至1998年期间因单侧小肾肿瘤而接受保肾手术的53例患者的手术结果进行回顾性分析。

材料与方法

按照欧洲癌症研究与治疗组织(EORTC)的指导方针,在术后对患者进行了20至143个月的随访。我们共治疗了25名女性和28名男性,平均年龄为53.7岁。其中10例患者接受了部分肾切除术,其余43例患者的肿瘤被摘除。

结果

无复发和转移的平均观察时间为63.8个月,5.7%的患者出现了与局部疾病相关的复发,1.9%的患者出现了远处复发。

结论

  1. 对于直径达4厘米的肿瘤,保肾手术是根治性手术的一种安全替代方案。2. 我们患者的前瞻性10年生存率为98%,其中92%的患者无复发或转移。3. 肿瘤的偶然诊断以及低分期和低分级是阳性预后因素。

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