Gyllerup S
Husensjö Group Practice, Helsingborg, Sweden.
Int J Circumpolar Health. 2000 Oct;59(3-4):160-3.
In many European countries there is a tendency towards higher coronary mortality in the northern parts of the country. Furthermore the highest coronary mortality rates are found in the colder parts of Europe. We studied the regional variation in coronary mortality in the 284 Swedish municipalities during a ten-year period and the relation to the cold exposure in each municipality during the same time period.
Mortality rates for each municipality were acquired from the death certificates and indirectly standardised against the country. Temperature readings from measurements 5 times a day during daytime were used to form a cold index. We also compensated for wind chill by using Siples wind chill index. Multiple regression models were used. Second degree polynomials were used for the explanatory variables.
There was a strong relation between the cold exposure in a municipality and coronary mortality. The cold index alone could explain 39% of the regional variation in coronary mortality. In a multiple regression model, cold index was the strongest explanatory variable. The coronary mortality in the coldest decile of the population was 40% higher than in the country as a whole.
There is a strong regional association between cold exposure and coronary mortality in Sweden. However, in this type of study, it is not possible to determine whether this association is a causal one or not.
在许多欧洲国家,该国北部地区的冠心病死亡率有上升趋势。此外,欧洲最冷的地区冠心病死亡率最高。我们研究了瑞典284个市政当局在十年期间冠心病死亡率的区域差异,以及同一时期每个市政当局的寒冷暴露情况之间的关系。
从死亡证明中获取每个市政当局的死亡率,并与全国数据进行间接标准化。利用白天每天5次测量的温度读数形成一个寒冷指数。我们还使用西普尔斯风冷指数来补偿风寒。使用多元回归模型。解释变量采用二次多项式。
一个市政当局的寒冷暴露与冠心病死亡率之间存在很强的关系。仅寒冷指数就能解释冠心病死亡率区域差异的39%。在多元回归模型中,寒冷指数是最强的解释变量。最冷十分位数人群的冠心病死亡率比全国总体水平高40%。
在瑞典,寒冷暴露与冠心病死亡率之间存在很强的区域关联。然而,在这类研究中,无法确定这种关联是否为因果关系。