Jones T D, Plassmann P
School of Computing, University of Glamorgan, Pontypridd, UK.
IEEE Trans Med Imaging. 2000 Dec;19(12):1202-10. doi: 10.1109/42.897812.
Leg ulcers are chronic skin wounds that affect many people and take a long time to heal. The progress of wound healing and the effect of clinical treatments can be monitored partly by measuring the area of the wound. Measurements taken via manually based methods, such as using a computer pointing device to delineate the wound boundary in a digitized image, suffer from variations due to manual dexterity and differences of opinion between observers. An active contour model is presented that models the contour using piecewise B-spline arcs and uses the minimax principle to adaptively regularize the contour according to the local conditions in the wound image. The model makes use of the existing manual delineation process in order to initialize the solution and is shown to reduce the effect of the inherent variations upon the repeatability and consistency of area measurements in many cases.
腿部溃疡是一种影响众多人群且愈合时间漫长的慢性皮肤伤口。伤口愈合的进程以及临床治疗的效果可部分通过测量伤口面积来监测。通过基于手动的方法进行测量，比如使用计算机指针设备在数字化图像中描绘伤口边界，会因手动操作的灵活性以及观察者之间的意见分歧而产生差异。本文提出了一种活动轮廓模型，该模型使用分段B样条曲线对轮廓进行建模，并利用极小极大原理根据伤口图像的局部情况自适应地对轮廓进行正则化。该模型利用现有的手动描绘过程来初始化解决方案，并且在许多情况下已证明可减少固有差异对面积测量的可重复性和一致性的影响。
