Briat J F, Lobréaux S, Grignon N, Vansuyt G
Biochimie et Physiologie Moléculaire des Plantes, Centre National de la Recherche Scientifique URA 2133, Institut National de la Recherche Agronomique et Ecole Nationale Supérieure d'Agronomie, Montpellier, France.
Cell Mol Life Sci. 1999 Oct 1;56(1-2):155-66. doi: 10.1007/s000180050014.
Plant ferritins are key iron-storage proteins that share important structural and functional similarities with animal ferritins. However, specific features characterize plant ferritins, among which are plastid cellular localization and transcriptional regulation by iron. Ferritin synthesis is developmentally and environmentally controlled, in part through the differential expression of the various members of a small gene family. Furthermore, a strict requirement for plant ferritin synthesis regulation is attested to by alterations of the photosynthetic apparatus and of iron homeostasis in transgenic tobaccos overexpressing these proteins. Plant ferritin gene regulation appears to consist of a complex interplay of transcriptional and posttranscriptional mechanisms, involving cellular relays such as plant hormones, oxidative steps and Ser/Thr phosphatase.
植物铁蛋白是关键的铁储存蛋白，与动物铁蛋白在结构和功能上有重要的相似之处。然而，植物铁蛋白具有一些特定特征，其中包括质体细胞定位以及铁对其转录的调控。铁蛋白的合成受到发育和环境的控制，部分原因是一个小基因家族中各个成员的差异表达。此外，过表达这些蛋白的转基因烟草中光合装置和铁稳态的改变证明了对植物铁蛋白合成调控的严格要求。植物铁蛋白基因的调控似乎由转录和转录后机制的复杂相互作用组成，涉及细胞信号传导途径，如植物激素、氧化步骤和丝氨酸/苏氨酸磷酸酶。
