Chukwurah B K, Ajali U
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Science-University of Nigeria, Nsukka, Nigeria.
Boll Chim Farm. 2000 Nov-Dec;139(6):260-2.
Qualitative determination of cimetidine and famotidine by TLC using chloranilic acid as the detecting spray reagent was carried out in different elution systems. On spraying, coloured spots corresponding to the drugs were formed which were stable for over three hours. In a particular solvent system, a commercial sample gave the same Rf value as its corresponding pure reference sample without any interference from the excipient.
以氯冉酸作为检测喷雾试剂，采用薄层色谱法在不同洗脱系统中对西咪替丁和法莫替丁进行定性测定。喷雾后，形成了与药物相对应的有色斑点，这些斑点在三个多小时内保持稳定。在特定的溶剂系统中，市售样品的比移值与其相应的纯参比样品相同，且无辅料干扰。
