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气候及气候变化对药物和人类健康的影响。

Impacts of climate and climate change on medications and human health.

作者信息

Beggs P J

机构信息

Department of Physical Geography, Division of Environmental and Life Sciences, Macquarie University, Sydney, NSW 2109.

出版信息

Aust N Z J Public Health. 2000 Dec;24(6):630-2. doi: 10.1111/j.1467-842x.2000.tb00531.x.

DOI:10.1111/j.1467-842x.2000.tb00531.x
PMID:11215015
Abstract

OBJECTIVE

To examine impacts of climate and climate change on medications and human health.

METHODS

Literature review and analysis of MIMS.

RESULTS

Changed climate associated with the enhanced Greenhouse Effect (e.g. increased temperature) may lead to medication-related health impacts through deterioration of storage conditions, increased heat stress from medication-induced heat intolerance, and by influencing pharmacokinetics. Increases in UV radiation from stratospheric ozone depletion may increase the significance of medications that can lead to an increased sensitivity to the damaging effects of UV radiation (i.e. photosensitivity).

CONCLUSIONS AND IMPLICATIONS

Raising awareness of the impacts of climate on medications, and of climate-related side-effects, among both health care professionals and the public, should modify behaviour and therefore reduce the risks of such adverse impacts.

摘要

目的

研究气候及气候变化对药物和人类健康的影响。

方法

文献综述及对《医师案头参考手册》的分析。

结果

与温室效应增强相关的气候变化(如气温升高)可能通过储存条件恶化、药物引起的耐热性增加导致的热应激增加以及影响药代动力学,对与药物相关的健康产生影响。平流层臭氧消耗导致的紫外线辐射增加,可能会使那些会导致对紫外线辐射破坏作用敏感性增加(即光敏感性)的药物的重要性增加。

结论与启示

提高医疗保健专业人员和公众对气候对药物影响以及与气候相关副作用的认识,应能改变行为,从而降低此类不利影响的风险。

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