Satoh M, Hirabayashi Y, Seo N
Department of Anesthesiology, Jichi Medical School, Tochigi 329-0498.
Masui. 2000 Nov;49(11):1222-5.
We compared the efficacy of intravenous patient controlled analgesia of buprenorphine plus continuous thoracic epidural infusion of bupivacaine (IV-PCA group) with the efficacy of continuous thoracic epidural infusion of bupivacaine and buprenorphine (the TEA group). No patient in IV-PCA group required supplemental analgesics, while 90% of TEA group required supplemental intramuscular buprenorphine to relieve post-thoracotomy pain. In TEA group, 94% of the supplemental drugs were administered during night shifts. These results indicate that IV-PCA of buprenorphine combined with continuous thoracic epidural infusion of bupivacaine is more effective analgesic management than continuous TEA with buprenorphine and bupivacaine.
我们比较了布托啡诺静脉自控镇痛联合布比卡因持续胸段硬膜外输注（静脉-自控镇痛组）与布比卡因和布托啡诺持续胸段硬膜外输注（胸段硬膜外镇痛组）的疗效。静脉-自控镇痛组中无一例患者需要补充镇痛药，而胸段硬膜外镇痛组90%的患者需要补充肌肉注射布托啡诺以缓解开胸术后疼痛。在胸段硬膜外镇痛组中，94%的补充药物是在夜班期间给予的。这些结果表明，布托啡诺静脉-自控镇痛联合布比卡因持续胸段硬膜外输注比布托啡诺和布比卡因持续胸段硬膜外镇痛是更有效的镇痛管理方法。
