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Polysaccharide-based chiral stationary phases for high-performance liquid chromatographic enantioseparation.

作者信息

Yashima E

机构信息

Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Japan.

出版信息

J Chromatogr A. 2001 Jan 12;906(1-2):105-25. doi: 10.1016/s0021-9673(00)00501-x.

DOI:10.1016/s0021-9673(00)00501-x
PMID:11215883
Abstract

Recent developments of polysaccharide-based chiral stationary phases (CSPs) for the direct separation of enantiomers in high-performance liquid chromatography (HPLC) are mainly reviewed together with the results on mechanistic studies by means of chromatography, NMR and mass spectroscopies, and computational methods. Miscellaneous applications of polysaccharide derivatives to the newly developed, chiral dynamic high-performance liquid chromatography (DHPLC) for obtaining a nonracemic compound are also described.

摘要

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