Mertz D P, Wilk G, Koschnick R
Z Klin Chem Klin Biochem. 1975 Jan;13(1):13-5.
The renal excretion of silver was investigated in adult experimental persons of both sexes with normal or variously decreased kidney functions. Silver was measured by emission spectrum analysis. With an indifferent urinary flow of 4.71 plus or minus 2.5 (mean value with standard deviation) ml/min, the mean Ag-excretion was 0.653 plus or minus 0.432 ng/min for a standard 1.73 m2 body surface area. An apparent small increase in the Ag-excretion with increased rate of urine flow could not be statistically confirmed. The widely different Ag-excretion between individuals showed no dependence on the state of diuresis, or on kidney haemodynamic factors down to a decreased inulin clearance of less than 40 ml/min, and a decrease of the PAH clearance to values less than 200 ml/min.
对成年男女实验对象的肾脏排泄银的情况进行了研究，这些对象的肾功能正常或不同程度降低。通过发射光谱分析测定银含量。在平均尿流率为4.71±2.5（均值±标准差）毫升/分钟的情况下，对于标准体表面积1.73平方米，银的平均排泄量为0.653±0.432纳克/分钟。尿流率增加时银排泄量的明显小幅增加无法得到统计学证实。个体之间银排泄量的巨大差异与利尿状态无关，也与肾脏血流动力学因素无关，直至菊粉清除率降至低于40毫升/分钟，对氨基马尿酸清除率降至低于200毫升/分钟。
