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[胰腺炎的营养支持]

[Nutritional support in pancreatitis].

作者信息

Montejo González J C, López Martínez J

机构信息

Hospital Universitario 12 de Octubre, Madrid, España.

出版信息

Nutr Hosp. 2000;15 Suppl 1:86-92.

Abstract

Pancreatitis is an illness that can bring about nutritional changes in connection with the underlying cause, the metabolic reaction to stress or the limitations that this pathology may represent for the processes of digesting and absorbing nutrients or for tolerating the diet. Although nutritional support is well accepted as a therapeutic measure in patients with severe acute pancreatitis, there is some dispute over the route of administration. In patients with mild pancreatitis, the use of parenteral nutrition may be accompanied by an increase in complications, particularly due to catheter-related sepsis, but in severe cases, early parenteral nutrition has been associated with a lower incidence of complications and a drop in mortality. Although parenteral nutrition is the preferred conventional method for the nutritional support of patients with pancreatitis, enteral nutrition offers the advantages of being more physiological, safer and less costly, at the same time as it seems to have a favourable influence on the progress of the pancreatitis. For this reason, the current recommendations suggest the use of enteral nutrition via the jejunum in those cases where the severity of the pancreatitis indicates nutritional support. Further research is, however, necessary in this field to clarify the group of patients in which the benefits of nutritional support would be most evident, the most appropriate type of diet, and the role of enteral nutrition on the evolution, both locally and systemically, of the changes brought about by the inflammation of the pancreas.

摘要

胰腺炎是一种会因潜在病因、对应激的代谢反应或该病症可能对营养物质消化吸收过程或饮食耐受性造成的限制而引发营养变化的疾病。尽管营养支持作为重症急性胰腺炎患者的一种治疗措施已被广泛接受,但在给药途径方面仍存在一些争议。对于轻症胰腺炎患者,肠外营养的使用可能会伴随并发症增加,尤其是与导管相关的败血症,但在重症病例中,早期肠外营养与较低的并发症发生率及死亡率下降相关。尽管肠外营养是胰腺炎患者营养支持的首选传统方法,但肠内营养具有更符合生理、更安全且成本更低的优势,同时似乎对胰腺炎的病程有积极影响。因此,当前建议指出,在胰腺炎严重程度表明需要营养支持的情况下,应通过空肠进行肠内营养。然而,该领域仍需进一步研究,以明确营养支持益处最明显的患者群体、最合适的饮食类型以及肠内营养对胰腺炎症所致局部和全身变化演变的作用。

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