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[正常及微栓塞兔肺中棕榈酸-1-14-C在卵磷脂和磷脂含量中的整合(作者译)]

[Integration of palmitat-1-14-C in lecithine and phospholipid content in normal and micro-embolized rabbit lungs (author's transl)].

作者信息

von Wichert P, Wilke A, Gärtner U

出版信息

Anaesthesist. 1975 Feb;24(2):78-83.

PMID:1122017
Abstract

Glass microspheres were used for a diffuse pulmonary microembolisation, as a modell for shock lung. Microembolisation is regarded as an important factor in pathogenesis of shock lung. The capacity of lung for lecithin synthesis was measured with palmitat-1-14-C incorporation. The phospholipid content and the composition of the fatty acids of lecithin were investigated. From the results it was possible, that the surfactant system may alterated by the vascular blocking. The dates supporting the importance of microembolisation in pathogenesis of shock lung.

摘要

玻璃微球被用于进行弥漫性肺微栓塞,作为休克肺的一种模型。微栓塞被认为是休克肺发病机制中的一个重要因素。用棕榈酸-1-14-C掺入法测定肺合成卵磷脂的能力。研究了卵磷脂的磷脂含量和脂肪酸组成。从结果来看,有可能表面活性剂系统会因血管阻塞而改变。这些数据支持了微栓塞在休克肺发病机制中的重要性。

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