Korshunova O V, Kafarskaia L I, Efimov B A, Makarov O V, Pinegin B V, Korshunov V M
Russian State Medical University, Institute of Medico-Social Rehabilitation, Research Institute of Immunology, Moscow, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2000 Sep-Oct(5):69-72.
15 pregnant women with pregnancy lasting 28-32 weeks, whose medico-laboratory data (the positive result of the amino test, high pH value and the detection of "key" cells) suggested the presence of bacterial vaginosis, were placed under observation. The bacteriological study of vaginal microflora in all these women revealed pronounced disturbances simultaneously with the development of intestinal dysbacteriosis. The local application of the bacterial preparation "Zhlemik" containing freeze-dried live lactic acid bacteria of vaginal origin and the oral administration of lactic acid bifidumbacterin containing live bifidobacteria of intestinal origin permitted the successful restoration of vaginal and intestinal microbiocenosis. The capacity of biotherapeutic preparations for inducing non-specific immunostimulation led to a significant rise in the levels of IgA, IgM and IgG in vaginal secretions.
15名怀孕28至32周的孕妇，其医学实验室数据（氨基酸试验阳性结果、高pH值以及“关键”细胞的检测）提示存在细菌性阴道病，对她们进行了观察。对所有这些女性阴道微生物群的细菌学研究发现，在肠道菌群失调发展的同时，存在明显的紊乱。局部应用含有冻干阴道源活乳酸菌的细菌制剂“Zhlemik”，并口服含有肠道源活双歧杆菌的乳酸双歧杆菌素，成功恢复了阴道和肠道微生物群落。生物治疗制剂诱导非特异性免疫刺激的能力导致阴道分泌物中IgA、IgM和IgG水平显著升高。
