Kozlova N V, Zhilenko M I, Dymov V O, Aleksandrova A V
Antibiot Khimioter. 1994 Jun;39(6):39-43.
Microflora of the vaginal mucosa was investigated bacteriologically in 44 pregnant women at the pregnancy term of 27-28 weeks. It was shown that in half of the women the vaginal microbiocenosis was within the normal and did not depend on urogynecological diseases in the case histories. In the women with impaired microbiocenosis the level of the impairment depended on gynecological diseases in the case histories. In the pregnant women without urogynecological diseases only slightly pronounced changes in the vaginal microbiocenosis were detected. The prophylactic use of eubiotics (bifidumbacterin and lactobacterin) was not efficient. In the women with urogynecological diseases in the case histories the levels of the microbiocenosis impairment were different. The prophylactic use of the eubiotics was efficient when the changes in the vaginal microbiocenosis were slightly pronounced or marked. When the changes were extreme the prophylactic use of the eubiotics failed.
对44名妊娠27 - 28周的孕妇的阴道黏膜微生物群进行了细菌学研究。结果表明，半数孕妇的阴道微生物群落处于正常范围内，且与病史中的泌尿妇科疾病无关。在微生物群落受损的孕妇中，受损程度取决于病史中的妇科疾病。在无泌尿妇科疾病的孕妇中，仅检测到阴道微生物群落有轻微变化。预防性使用益生菌（双歧杆菌素和乳酸菌素）无效。在病史中有泌尿妇科疾病的孕妇中，微生物群落受损程度各不相同。当阴道微生物群落变化轻微或明显时，预防性使用益生菌有效。当变化极端时，预防性使用益生菌失败。
