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[血管外层和视网膜疾病中免疫缺陷的临床实验室前诊断]

[Clinical pre-laboratory diagnosis of immune deficiency in diseases of the vascular coating and retina].

作者信息

Teplinskaia L E, Arkhipova L T, Kaliberdina A F

出版信息

Vestn Oftalmol. 1991 Jan-Feb;107(1):23-5.

PMID:2035199
Abstract

The authors analyze the results of prelaboratory diagnosis of immunologic insufficiency in 948 patients with various clinical forms of endogenic uveitis and retinovasculitis; the diagnosis was based on the totality of clinical signs and ther combinations, summed up in a universal diagnostic chart developed at the Institute of Immunology of the RSFSR Ministry of Health. Immunologic insufficiency was diagnosed in 67.5 percent of uveitis patients mainly in the presence of infectious or autoimmune syndromes developing, as is well known, in depression of T cellular immunity. This is practically valuable for the development of pathogenetic treatment of these grave patients, whose multiple-modality treatment should include immunostimulants and immunomodulators.

摘要

作者分析了948例患有各种临床类型的内因性葡萄膜炎和视网膜血管炎患者的免疫功能不全的实验室前诊断结果;诊断基于临床体征及其组合的总体情况,这些都总结在俄罗斯联邦卫生部免疫研究所制定的通用诊断图表中。67.5%的葡萄膜炎患者被诊断为免疫功能不全,主要是在出现感染或自身免疫综合征时,众所周知,这些综合征是在T细胞免疫抑制的情况下发生的。这对于这些重症患者的病因治疗的开展具有实际价值,他们的多模式治疗应包括免疫刺激剂和免疫调节剂。

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