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一种用于检测多通道脑电图和事件相关电位记录中电解质桥的便捷方法。

A convenient method for detecting electrolyte bridges in multichannel electroencephalogram and event-related potential recordings.

作者信息

Tenke C E, Kayser J

机构信息

Department of Biopsychology, Unit 50, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY, USA.

出版信息

Clin Neurophysiol. 2001 Mar;112(3):545-50. doi: 10.1016/s1388-2457(00)00553-8.

Abstract

Dense electrode arrays offer numerous advantages over single channel electroencephalogram/event-related potential (EEG/ERP) recordings, but also exaggerate the influence of common error sources arising from the preparation of scalp placements. Even with conventional low density recordings (e.g. 30-channel Electro-Cap), over-application of electrode gel may result in electrolyte leakage and create low impedance bridges, particularly at vertically-aligned sites (e.g. inferior-lateral). The ensuing electrical short produces an artificial similarity of ERPs at neighboring sites that distorts the ERP topography. This artifact is not immediately apparent in group averages, and may even go undetected after visual inspection of the individual ERP waveforms. Besides adding noise variance to the topography, this error source also has the capacity to introduce systematic, localized artifacts (e.g. add or remove evidence of lateralized activity). Electrolyte bridges causing these artifacts can be easily detected by a simple variant of the Hjorth algorithm (intrinsic Hjorth), in which spatial interelectrode distances are replaced by an electrical analog of distance (i.e. the variances of the difference waveforms for all pairwise combinations of electrodes). When a low impedance bridge exists, the Hjorth algorithm identifies all affected sites as flat lines that are readily distinguishable from Hjorth waveforms at unbridged electrodes.

摘要

密集电极阵列相较于单通道脑电图/事件相关电位(EEG/ERP)记录具有诸多优势,但也会夸大头皮电极放置准备过程中常见误差源的影响。即使采用传统的低密度记录方式(例如30通道的Electro - Cap),电极凝胶涂抹过多也可能导致电解质泄漏并形成低阻抗桥接,尤其是在垂直对齐的部位(如下外侧)。由此产生的电短路会使相邻部位的ERP出现人为的相似性,从而扭曲ERP地形图。这种伪迹在组平均中不会立即显现,甚至在对单个ERP波形进行目视检查后也可能未被发现。除了增加地形图的噪声方差外,这个误差源还能够引入系统性的局部伪迹(例如增加或消除偏侧化活动的证据)。通过Hjorth算法的一个简单变体(固有Hjorth)可以轻松检测到导致这些伪迹的电解质桥接,其中电极间的空间距离被距离的电学模拟量(即所有电极对组合的差值波形的方差)所取代。当存在低阻抗桥接时,Hjorth算法会将所有受影响的部位识别为平线,这与未桥接电极处的Hjorth波形很容易区分开来。

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