Klimov A N, Nikiforova A A, Tchistiakova A M
Biochim Biophys Acta. 1975 Jan 24;380(1):76-80. doi: 10.1016/0005-2760(75)90046-6.
The inhibition of the lecithin-cholesterol acyltransferase reaction in human plasma by the polyene antibiotics, levorine and amphotericin B, has been demonstrated by in vitro experiments. It is suggested that the inhibition of the esterification reaction is the result of interaction between polyenes and non-esterified cholesterol.
