软性膀胱镜检查前预防性使用抗生素的问题。
The issue of prophylactic antibiotics prior to flexible cystoscopy.
作者信息
Rané A, Cahill D, Saleemi A, Montgomery B, Palfrey E
机构信息
Department of Urology, Frimley Park Hospital, Frimley, UK.
出版信息
Eur Urol. 2001 Feb;39(2):212-4. doi: 10.1159/000052438.
OBJECTIVE
The aim of this study was to determine whether single-dose parenteral antibacterial therapy significantly alters the rate of infection in patients undergoing flexible cystourethroscopy.
PATIENTS AND METHODS
162 patients were studied prospectively having either received parenteral antibacterial chemoprophylaxis prior to flexible cystourethroscopy or not. Pre- and postprocedure mid stream samples of urine (MSSU) were obtained to objectively evaluate the presence of infection.
RESULTS
Gentamicin prophylaxis reduced the rate of post-cystoscopy-positive MSSUs from 21 to 5%.
CONCLUSION
The surprisingly high rate of infection after flexible cystoscopy was significantly reduced by a single dose of gentamicin.
目的
本研究旨在确定单剂量胃肠外抗菌治疗是否会显著改变接受软性膀胱尿道镜检查患者的感染率。
患者与方法
前瞻性研究了162例患者，这些患者在接受软性膀胱尿道镜检查之前，有的接受了胃肠外抗菌预防，有的未接受。获取术前和术后的中段尿样本（MSSU）以客观评估感染情况。
结果
庆大霉素预防使膀胱镜检查后MSSU阳性率从21%降至5%。
结论
单剂量庆大霉素显著降低了软性膀胱镜检查后令人惊讶的高感染率。
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