Barry J C, Loewen N
Augenklinik Abt. II, Pathophysiologie des Sehens und Neuroophthalmologie, Universitäts-Klinikum Tübingen, Schleichstr. 12, D-72076 Tübingen.
Klin Monbl Augenheilkd. 2001 Jan;218(1):26-30. doi: 10.1055/s-2001-11257.
Because of its advantages, topical cyclopentolate is often preferred over the gold standard, atropine. The purpose of the study was to obtain an overview over current cycloplegia protocols and to estimate the likelihood of severe complications due to the use of cycloplegics.
A questionnaire was sent to 107 German-speaking centres with a supposed high cycloplegia frequency.
57 centres answered, whereby 1,112 cumulated years of experience with cycloplegia were available for analysis. The frequency of cycloplegias varied between 2 and 180/week/centre, median 25/week/centre. A cumulated amount of 1.7 million cycloplegias was computed. The average extrapolated experience with cycloplegia was 49,000 cycloplegias/30 years. Severe complications which would cause a medical follow up of several hours or which led to a follow up in a ward were named 47 times and 2 times, respectively.
During 30 years of a cycloplegia career with an average of 34 cycloplegias/week, one may expect 2-10 severe complications. In current practice, the patient risk of severe complications is very small. Health care professionals and parents should be informed about the frequent occurrence of light side effects in order to reach a good compliance with cycloplegia.
由于其优势，局部用环喷托酯通常比金标准药物阿托品更受青睐。本研究的目的是全面了解当前的睫状肌麻痹方案，并评估使用睫状肌麻痹剂导致严重并发症的可能性。
向107个德语区、推测睫状肌麻痹频率较高的中心发送了一份调查问卷。
57个中心进行了回复，据此可对1112年累计的睫状肌麻痹经验进行分析。各中心每周的睫状肌麻痹次数在2至180次之间，中位数为每周25次。据此计算出累计睫状肌麻痹次数达170万次。推测睫状肌麻痹的平均经验为每30年49000次。分别有47次和2次提到了会导致数小时医学随访或需在病房进行随访的严重并发症。
在从事睫状肌麻痹工作的30年中，平均每周进行34次睫状肌麻痹操作的情况下，预计会出现2至10次严重并发症。在当前的实践中，患者出现严重并发症的风险非常小。应告知医护人员和家长轻度副作用的频繁发生情况，以便患者更好地配合睫状肌麻痹治疗。
