Para-O-methylation of the catecholamines in neuroblastoma.
作者信息
Verheyden R, Ebinger G
出版信息
Clin Chim Acta. 1975 Jan 20;58(2):181-4. doi: 10.1016/s0009-8981(75)80011-8.
PMID:1122641
Abstract
By means of thin-layer chromatographic methods, iso-homovanillic acid (iso-HVA), iso-vanillactic acid (iso-VLA) and iso-vanilmandelic acid (iso-VMA) were determined in the urine of 10 children with neuroblastoma. The mean excretion of iso-HVA was 10.1% of total HVA excretion. Three patients excreted VLA; in their urine no iso-VLA was detected with certainty. All patients excreted high amounts of VMA; there was no detectable excretion of iso-VMA. Those results suggest that para-O-methylation could be limited to dopamine catabolism.
摘要
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引用本文的文献
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Thin-layer chromatography for diagnosis of secreting neuroblastoma.
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