Tran T D, Kubota M, Takeshita K, Yanagisawa M, Sakakihara Y
Department of Pediatrics, the University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan.
Brain Dev. 2001 Mar;23(1):54-7. doi: 10.1016/s0387-7604(00)00199-6.
A patient with acute necrotizing encephalophathy (ANE) following varicella infection with a good prognosis is reported. A somatosensory evoked magnetic field (SEF) study using a 37-channel-magnetoencephalography system demonstrated normal latency and strength of the first component (N20m) elicited by median nerve stimulation, despite bilateral symmetrical thalamic lesions on MRI. The normal SEF findings and the good prognosis suggested a reversible breakdown of the blood-brain barrier, and an edematous process as the brain pathology. Furthermore, our results support the idea of distinct generators for the three earliest cortical SEF components (N20m, P30m, N45m).
报告了1例水痘感染后发生急性坏死性脑病（ANE）且预后良好的患者。使用37通道脑磁图系统进行的体感诱发电场（SEF）研究表明，尽管MRI显示双侧丘脑对称性病变，但正中神经刺激诱发的第一成分（N20m）的潜伏期和强度正常。正常的SEF结果和良好的预后提示血脑屏障的可逆性破坏以及作为脑病理改变的水肿过程。此外，我们的结果支持最早的三个皮质SEF成分（N20m、P30m、N45m）具有不同发生器的观点。
