Burnett R T, Smith-Doiron M, Stieb D, Raizenne M E, Brook J R, Dales R E, Leech J A, Cakmak S, Krewski D
Environmental Health Directorate, Health Canada, 200 Environmental Health Center, Tunney's Pasture, Ottawa, Ontario, Canada K1A OL2.
Am J Epidemiol. 2001 Mar 1;153(5):444-52. doi: 10.1093/aje/153.5.444.
To clarify the health effects of ozone exposure in young children, the authors studied the association between air pollution and hospital admissions for acute respiratory problems in children less than 2 years of age during the 15-year period from 1980 to 1994 in Toronto, Canada. The daily time series of admissions was adjusted for the influences of day of the week, season, and weather. A 35% (95% confidence interval: 19%, 52%) increase in the daily hospitalization rate for respiratory problems was associated with a 5-day moving average of the daily 1-hour maximum ozone concentration of 45 parts per billion, the May-August average value. The ozone effect persisted after adjustment for other ambient air pollutants or weather variables. Ozone was not associated with hospital admissions during the September-April period. Ambient ozone levels in the summertime should be considered a risk factor for respiratory problems in children less than 2 years of age.
为了阐明幼儿接触臭氧对健康的影响，作者研究了1980年至1994年这15年间，加拿大多伦多2岁以下儿童空气污染与急性呼吸道疾病住院之间的关联。对住院情况的每日时间序列进行了调整，以消除星期、季节和天气的影响。每日呼吸道疾病住院率增加35%（95%置信区间：19%，52%）与每日1小时最大臭氧浓度（45 ppb）的5天移动平均值相关，该值为5月至8月的平均值。在对其他环境空气污染物或天气变量进行调整后，臭氧效应依然存在。9月至4月期间，臭氧与住院无关。夏季环境臭氧水平应被视为2岁以下儿童呼吸道疾病的一个风险因素。
