Magzamen Sheryl, Moore Brianna F, Yost Michael G, Fenske Richard A, Karr Catherine J
Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado (Drs Magzamen, Moore); Department of Environmental and Occupational Health Sciences (Drs Magzamen, Yost, Fenske, Karr); Department of Epidemiology (Dr Karr), University of Washington School of Public Health; Department of Pediatrics, University of Washington School of Medicine (Dr Karr), Seattle, Washington.
J Occup Environ Med. 2017 Jul;59(7):624-630. doi: 10.1097/JOM.0000000000001042.
We evaluated the effects of ozone on respiratory-related hospital admissions in three counties in Washington State from 1990 to 2006. We further examined vulnerability to ozone by key demographic factors.
Using linked hospital admission and ambient monitoring data, we estimated the age-, sex-, and health insurance-stratified associations between ozone (0 to 3 days' lag) and respiratory-related hospital admissions in King, Spokane, and Clark County, Washington.
The adjusted relative risk (RR) for a 10 ppb increase in ozone at 3 days' lag was 1.04 (95% confidence interval [CI]: 1.02, 1.07) for Clark County, 1.03 (95% CI: 1.01, 1.05) for Spokane County, and 1.02 (95% CI: 1.01, 1.03) for King County. There was consistent evidence of effect modification by age.
Ozone at levels below federal standards contributes to respiratory morbidity among high-risk groups in Washington.
我们评估了1990年至2006年华盛顿州三个县臭氧对呼吸道相关住院率的影响。我们还通过关键人口统计学因素进一步研究了对臭氧的易感性。
利用关联的住院和环境监测数据，我们估计了华盛顿州金县、斯波坎县和克拉克县臭氧（滞后0至3天）与呼吸道相关住院率之间按年龄、性别和健康保险分层的关联。
克拉克县滞后3天臭氧浓度每增加10 ppb，调整后的相对风险（RR）为1.04（95%置信区间[CI]：1.02，1.07）；斯波坎县为1.03（95%CI：1.01，1.05）；金县为1.02（95%CI：1.01，1.03）。有一致的证据表明年龄对效应有修饰作用。
低于联邦标准水平的臭氧会导致华盛顿州高危人群的呼吸道发病。
