Hiltunen L A, Keinänen-Kiukaanniemi S M
Department of Public Health Science and General Practice, University of Oulu, Finland.
Scand J Public Health. 2000 Dec;28(4):266-9.
Population data suggest that a fasting blood glucose level of > or = 6.1 mmol/l corresponds best to a two-hour blood glucose level of > or = 11.1 mmol/l, which is associated with an increased risk of developing microvascular complications. The proposed new criteria, and the WHO 1985 criteria for diabetes, were applied in an elderly population, which underwent a two-hour oral glucose tolerance test. The prevalence of diabetes was higher when the proposed new criteria were used than when the old criteria were used. In calculating the prevalence of diabetes, the fasting blood glucose > or = 6.1 mmol/l corresponded better to the combination of fasting and/or two-hour values than did fasting blood glucose > or = 6.7 mmol/l. The prevalence obtained by using either of these fasting values alone or in combination with two-hour values corresponded poorly to that obtained by using mere two-hour blood glucose values.
人群数据表明,空腹血糖水平≥6.1 mmol/L最能对应两小时血糖水平≥11.1 mmol/L,而这与微血管并发症发生风险增加相关。在接受两小时口服葡萄糖耐量试验的老年人群中应用了提议的新诊断标准以及世界卫生组织1985年的糖尿病诊断标准。使用提议的新诊断标准时糖尿病患病率高于使用旧标准时。在计算糖尿病患病率时,空腹血糖≥6.1 mmol/L比空腹血糖≥6.7 mmol/L更能与空腹和/或两小时血糖值的组合情况相匹配。单独使用这两种空腹血糖值中的任何一种或与两小时血糖值结合使用所得到的患病率,与仅使用两小时血糖值所得到的患病率相关性较差。