Maheshwari M C, Jeavons P M
Epilepsia. 1975 Mar;16(1):127-31. doi: 10.1111/j.1528-1157.1975.tb04729.x.
Thirty-nine children, seen between 1960 and 1973, showed suppression-burst activity in their original EEG recordings. Follow-up information was available for 19 girls and 10 boys. Suppression-burst activity was seen at a mean age of 4 months. Most of the children (86 per cent) had infantile spasms, and 96 per cent were severely retarded on presentation. Fifteen died (52 per cent), 9 of them before the age of 2, and all had severe retardation and neurological abnormalities. Of the 14 survivors, only 1 attends a normal school (she was only mildly retarded on presentation), 71 per cent are severely retarded, 71 per cent have neurological abnormalities, and 60 per cent continue to have fits. Although hypsarrhythmia itself is not necessarily associated with a bad prognosis, the finding of suppression-burst activity certainly implies a grave outlook.
1960年至1973年间诊治的39名儿童，其原始脑电图记录显示有抑制-爆发活动。有19名女孩和10名男孩的随访信息。抑制-爆发活动见于平均年龄4个月时。大多数儿童（86%）有婴儿痉挛症，96%在初诊时严重发育迟缓。15名儿童死亡（52%），其中9名在2岁前死亡，所有死亡儿童均有严重发育迟缓和神经异常。14名存活者中，只有1名能正常上学（她初诊时仅轻度发育迟缓），71%严重发育迟缓，71%有神经异常，60%仍有癫痫发作。虽然高度失律本身不一定与不良预后相关，但抑制-爆发活动的发现肯定预示着预后不良。
