实验啮齿动物的临床病理学与样本采集

Department of Animal Resources, University of California, Santa Barbara, California, USA.

Vet Clin North Am Exot Anim Pract. 1999 Sep;2(3):565-90, vi. doi: 10.1016/s1094-9194(17)30111-1.

Common laboratory rodents have always been a favorite choice as a pet. Although diagnostic clinical pathology has not been viewed as practical for the rodent patient, current advances in technology make processing of small samples possible. Cultivation of the technical skills necessary for rodent sample collection has the potential to improve the standard of rodent veterinary care. This article provides an overview of rodent sample collection techniques, hematology, clinical biochemistry, serology, and clinical pathology of other tissues and fluids for laboratory rodents. General principles of clinical pathology can be applied across species. This article emphasizes the subtleties of the different rodent species which may impact diagnostic interpretation.

常见的实验用啮齿动物一直是备受青睐的宠物选择。尽管诊断性临床病理学对啮齿动物患者而言一直被认为不实用，但当前技术的进步使小样本处理成为可能。培养啮齿动物样本采集所需的技术技能有潜力提高啮齿动物兽医护理的标准。本文概述了实验室啮齿动物的样本采集技术、血液学、临床生物化学、血清学以及其他组织和体液的临床病理学。临床病理学的一般原则可适用于所有物种。本文强调了不同啮齿动物物种可能影响诊断解读的细微差别。