嗅结节中的多巴胺代谢
Dopamine metabolism in the tuberculum olfactorium.
作者信息
Wilk S, Watson E, Glick S D
出版信息
Eur J Pharmacol. 1975 Jan;30(1):117-20. doi: 10.1016/0014-2999(75)90212-5.
PMID:1122932
Abstract
The occurrence of the major dopamine metabolites, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the tuberculum olfactorium of the rat was demonstrated by gas chromatography. The ratio of DOPAC to HVA in the tuberculum olfactorium was greater than the ratio of these metabolites in the striatum. The effect of pargyline and probenecid on dopamine metabolite levels was similar for both the tuberculum olfactorium and striatum.
摘要
通过气相色谱法证实了大鼠嗅结节中主要多巴胺代谢产物3,4-二羟基苯乙酸（DOPAC）和高香草酸（HVA）的存在。嗅结节中DOPAC与HVA的比例高于纹状体中这些代谢产物的比例。帕吉林和丙磺舒对嗅结节和纹状体中多巴胺代谢产物水平的影响相似。
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