Clathrin uncoating: Auxilin comes to life.
作者信息
Lemmon S K
机构信息
Department of Molecular Biology and Microbiology, Case Western Reserve, University School of Medicine, 10900 Euclid Avenue, Cleveland, Ohio 44106-4960, USA.
出版信息
Curr Biol. 2001 Jan 23;11(2):R49-52. doi: 10.1016/s0960-9822(01)00010-0.
Abstract
The DnaJ protein auxilin has been extensively studied in vitro as a cofactor for uncoating clathrin-coated vesicles by the chaperone Hsc70. Recent studies provide the first evidence that auxilin plays this role in vivo, and work on a new mammalian auxilin suggests the protein may have more complex cellular functions.
摘要
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