Shimizu H, Ueda T, Kashima I, Mitsumaru A, Tsutsumi K, Enoki C, Iino Y, Koizumi K, Kawada S
Department of Surgery, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.
Jpn J Thorac Cardiovasc Surg. 2001 Jan;49(1):62-6. doi: 10.1007/BF02913126.
The treatment for a ruptured thoracic aortic aneurysm remains controversial. This study was undertaken to assess the outcome from surgery.
Between 1993 and 1998, we have performed 19 operations for a ruptured thoracic aortic aneurysm. Patients with an impending rupture or a chronic false aneurysm were excluded. There were 11 men and 8 women, with a mean age of 70.5 +/- 6.7 years. The aneurysm was caused by dissection in 8 patients. Of these, 7 were acute (Stanford type A, 6; type B, 1), and the other one was chronic (type B). Aortic rupture occurred into the pericardial cavity (n = 7), into the left lung (n = 6), the mediastinum (n = 3), the pleural cavity (n = 2), or into the esophagus (n = 1). Severely unstable hemodynamics were noted in 12 patients with a rupture into the pericardium, mediastinum, or pleural cavity (Group A). Inotropic support was required in each of these patients. Metabolic acidosis developed all but 1 patient. The 7 patients with a rupture into the lung or esophagus coughed or vomited blood (Group B). The operative approach was anterior (n = 17) or lateral (n = 2). Grafts were placed in the ascending aorta (n = 4), ascending and transverse arch aorta (n = 7), transverse arch aorta (n = 3), or in the descending thoracic aorta (n = 5). Selective cerebral perfusion was used in 13 patients.
There were 5 hospital deaths (26.3%). The postoperative complications included central nervous system dysfunction (n = 3), low cardiac output syndrome or cardiac arrhythmias (n = 3), respiratory failure (n = 4), acute renal failure (n = 1), and local or systemic infections (n = 4). The perioperative event-free rate was 36.8% overall, 25% in Group A, and 57.1% in Group B.
Patients with unstable hemodynamics require prompt operative intervention. Rupture into the esophagus is associated with a high mortality rate. Rupture in a thoracic aortic aneurysm can be successfully treated with emergency surgery.
胸主动脉瘤破裂的治疗仍存在争议。本研究旨在评估手术治疗的结果。
1993年至1998年间,我们对19例胸主动脉瘤破裂患者进行了手术。即将破裂或慢性假性动脉瘤患者被排除。患者中男性11例,女性8例,平均年龄70.5±6.7岁。8例患者的动脉瘤由夹层引起。其中,7例为急性(斯坦福A型6例;B型1例),另1例为慢性(B型)。主动脉破裂进入心包腔(7例)、左肺(6例)、纵隔(3例)、胸腔(2例)或食管(1例)。12例破裂进入心包、纵隔或胸腔的患者出现严重不稳定的血流动力学(A组)。这些患者均需要使用血管活性药物支持。除1例患者外,其余患者均出现代谢性酸中毒。7例破裂进入肺或食管的患者咳嗽或咯血(B组)。手术入路为前路(17例)或侧路(2例)。人工血管分别置于升主动脉(4例)、升主动脉和横弓(7例)、横弓(3例)或降胸主动脉(5例)。13例患者采用选择性脑灌注。
5例患者术后死亡(26.3%)。术后并发症包括中枢神经系统功能障碍(3例)、低心排血量综合征或心律失常(3例)、呼吸衰竭(4例)、急性肾衰竭(1例)以及局部或全身感染(4例)。围手术期无事件发生率总体为36.8%,A组为25%,B组为57.1%。
血流动力学不稳定的患者需要及时进行手术干预。破裂进入食管与高死亡率相关。胸主动脉瘤破裂可通过急诊手术成功治疗。