Innocenti A
U.O. Igiene e Salute nei Luoghi di Lavoro, USL 3 Pistoia, Regione Toscana, Villa Ankurj, via provinciale lucchese, 51010 Massa e Cozzile, PT.
Med Lav. 2000 Nov-Dec;91(6):565-74.
The question of appropriate exposure standards for wood dust is addressed by reference to the major health effects, especially sino-nasal cancer, that have been investigated. A review of several key papers on wood dust exposure permits some associations to be made between exposure data and effects, particularly impaired/suppressed nasal mucociliary clearance, according to which it may be suggested, based on available evidence, that a standard of 1.5-2 mg/m3 of total suspended wood dust could reasonably protect against the observed effects. Moreover, data from the literature show that reducing personal wood dust exposures to below 2 mg/m3 is accomplished relatively easily, whereas reducing exposures to below 1 mg/m3 is considerably more difficult and expensive. The exposure level of 1.5-2 mg/m3 is suggested for all wood dusts; it does not seem reasonable at the present time to distinguish between hardwood and softwood because many of the important mortality studies report results based on patients with mixed exposures. The threshold exposure value of 5 mg/m3 for hardwood proposed from 1/1/2003 by Law 66/2000 is deemed to be too high as a health-based occupational exposure limit.
通过参考已调查的主要健康影响，尤其是鼻窦癌，来探讨木尘的适当接触标准问题。对几篇关于木尘接触的关键论文进行综述后，可以在接触数据和影响之间建立一些关联，特别是鼻黏膜纤毛清除功能受损/受抑制，据此，根据现有证据，建议总悬浮木尘标准为1.5 - 2毫克/立方米可合理预防所观察到的影响。此外，文献数据表明，将个人木尘接触量降低到2毫克/立方米以下相对容易，而将接触量降低到1毫克/立方米以下则要困难得多且成本更高。建议所有木尘的接触水平为1.5 - 2毫克/立方米；目前区分硬木和软木似乎不合理，因为许多重要的死亡率研究报告的结果是基于混合接触的患者。2000年第66号法律自2003年1月1日起提出的硬木5毫克/立方米的接触阈值被认为作为基于健康的职业接触限值过高。
