Pisaniello D L, Connell K E, Muriale L
Department of Community Medicine, University of Adelaide, South Australia.
Am Ind Hyg Assoc J. 1991 Nov;52(11):485-92. doi: 10.1080/15298669191365090.
A survey of time-weighted average (TWA) personal inhalable dust exposures for woodworkers in 15 Australian furniture factories was undertaken. There was significant variation in the individual dust measurements with mean exposures of 3.2, 5.2, and 3.5 mg/m3 for wood machinists, cabinetmakers, and chair framemakers, respectively. Hardwoods, softwoods, and reconstituted woods are used in the industry, but only minor differences in mean exposures or particle size distributions were found for the broad categories. In addition, a modified British Medical Research Council respiratory questionnaire was used to obtain information about work-related symptoms and job activities. Compared with a control group, the woodworkers reported more eye, ear, and nasal problems, with the differences being statistically significant. However, among the woodworkers themselves, with the exception of several nasal symptoms, the prevalences of reported symptoms were poorly correlated with gravimetric measurements of personal dust exposure. The problem of selection bias in cross-sectional studies is discussed. For a mean TWA personal exposure of about 3 mg/m3, hardwood users were more likely to report nasal symptoms than users of reconstituted wood. The question of appropriate exposure standards for woods in general is addressed by reference to those important health effects, besides sino-nasal cancer, that have been investigated. Further exposure guidelines should be formulated for groups of woods that are known to cause a common health effect, such as nasal/respiratory sensitization.
对澳大利亚15家家具厂的木工进行了时间加权平均(TWA)个人可吸入粉尘暴露情况的调查。个体粉尘测量结果存在显著差异,木工、细木工和椅子框架制作工的平均暴露量分别为3.2、5.2和3.5毫克/立方米。该行业使用硬木、软木和再生木材,但在这几大类木材的平均暴露量或粒径分布方面仅发现细微差异。此外,还使用了一份经过修改的英国医学研究理事会呼吸问卷来获取与工作相关的症状和工作活动的信息。与对照组相比,木工报告的眼、耳和鼻问题更多,差异具有统计学意义。然而,在木工自身中,除了一些鼻部症状外,报告症状的患病率与个人粉尘暴露的重量测量结果相关性较差。讨论了横断面研究中的选择偏倚问题。对于平均TWA个人暴露量约为3毫克/立方米的情况,使用硬木的人比使用再生木材的人更有可能报告鼻部症状。除鼻窦癌外,还参考了已调查的那些重要健康影响,探讨了一般木材的适当暴露标准问题。对于已知会导致共同健康影响(如鼻/呼吸道致敏)的木材类别,应制定进一步的暴露指南。