一名心脏移植受者的皮肤链格孢菌病

Cutaneous alternariosis in a cardiac transplant recipient.

作者信息

Gilmour T K, Rytina E, O'Connell P B, Sterling J C

机构信息

Departments of Dermatology, Addenbrooke's Hospital, Cambridge, United Kingdom.

出版信息

Australas J Dermatol. 2001 Feb;42(1):46-9. doi: 10.1046/j.1440-0960.2001.00473.x.

DOI:10.1046/j.1440-0960.2001.00473.x

PMID:11233722

Abstract

A 55-year-old male cardiac transplant recipient presented with cutaneous nodules on the limbs caused by Alternaria alternata. Oral fluconazole 200 mg daily for 3 weeks was ineffective. Itraconazole 100 mg oral daily was ceased when hyperglycaemia developed. Individual lesions were successfully treated with either curettage and cautery or double freeze-thaw cryotherapy. Alternaria spp. are ubiquitous fungal saprophytes which may cause cutaneous infections particularly in immunocompromised patients.

摘要

一名55岁男性心脏移植受者出现由链格孢引起的四肢皮肤结节。每日口服200毫克氟康唑，持续3周，无效。当出现高血糖时，停止每日口服100毫克伊曲康唑。个别皮损通过刮除术和烧灼术或双重冻融冷冻疗法成功治愈。链格孢属是普遍存在的真菌腐生菌，可引起皮肤感染，尤其是在免疫功能低下的患者中。