Gerdsen R, Uerlich M, De Hoog G S, Bieber T, Horré R
Department of Dermatology, University of Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
Br J Dermatol. 2001 Sep;145(3):484-6. doi: 10.1046/j.1365-2133.2001.04382.x.
We describe a cardiac transplant patient who had human cutaneous alternariosis with a sporotrichoid distribution of skin lesions. In this patient identification of the causative organism Alternaria infectoria was achieved by sequencing the rDNA internal transcribed spacer domain. Treatment with itraconazole led to clinical resolution within 4 months.
我们描述了一名心脏移植患者,其患有皮肤链格孢菌病,皮肤损害呈孢子丝菌病样分布。在该患者中,通过对核糖体DNA内部转录间隔区进行测序鉴定出致病微生物感染链格孢菌。伊曲康唑治疗4个月内实现了临床缓解。