Werner M, Nordin P, Arnholm B, Elgefors B, Krantz I
Department of Infectious Diseases, Bords Hospital, Sweden.
Scand J Infect Dis. 2001;33(2):128-31. doi: 10.1080/003655401750065526.
Two hundred and fifty-three farmers and forest workers and 249 clerks from south-west Sweden were recruited to a cross-sectional seroprevalence study to find out if individuals working outdoors are more prone to acquire Borrelia burgdorferi infection than indoor workers and to find undiagnosed cases of Lyme borreliosis. The participants answered a questionnaire and blood specimens were collected to estimate the prevalence of antibodies to B. burgdorferi in each group. Sera were analysed with an enzyme-linked immunoassay technique to determine IgG antibodies to B. burgdorferi flagellum. The prevalence of B. burgdorferi antibodies was 7.6% in the farmers and forest workers vs. 5.3% in the clerks (adjusted odds ratio [age, sex] = 1.2 [95% confidence interval = 0.5-2.8]). One case of Lyme borreliosis was diagnosed. The positive predictive value of the antibody test was estimated to be 3% in the studied populations. B. burgdorferi infection is of low endemicity in south-west Sweden and is probably not an occupational risk among outdoor workers. Undiagnosed cases of Lyme borreliosis are uncommon. The test used is not acceptable for screening purposes.
来自瑞典西南部的253名农民和林业工人以及249名职员被招募到一项横断面血清流行率研究中，以确定从事户外工作的个体是否比室内工作者更容易感染伯氏疏螺旋体，以及发现未被诊断出的莱姆病病例。参与者回答了一份问卷，并采集了血液样本以估计每组中抗伯氏疏螺旋体抗体的流行率。采用酶联免疫吸附测定技术分析血清，以确定抗伯氏疏螺旋体鞭毛的IgG抗体。农民和林业工人中伯氏疏螺旋体抗体的流行率为7.6%，而职员中为5.3%（调整后的比值比[年龄、性别]=1.2[95%置信区间=0.5-2.8]）。确诊了1例莱姆病病例。在所研究的人群中，抗体检测的阳性预测值估计为3%。伯氏疏螺旋体感染在瑞典西南部的流行率较低，可能不是户外工作者的职业风险。未被诊断出的莱姆病病例并不常见。所使用的检测方法不适用于筛查目的。
