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[中毒性肺水肿大鼠血液和肺抗氧化系统的状态]

[Status of the blood and lung antioxidant system of the rat in toxic pulmonary edema].

作者信息

Pluzhnikov N N, Tiaptin A A, Lupachev Iu A, Zemlianoĭ A V, Varlashova M B, Torkunov P A, Novoselova N Iu

机构信息

Research Institute of Military Medicine, Defence Ministry of Russian Federation, St-Peterburg.

出版信息

Vopr Med Khim. 2000 Nov-Dec;46(6):564-73.

Abstract

The state of enzymatic and non-enzymatic components of antioxidant system and also lipid peroxidation processes in blood and lungs of rats with toxic pulmonary edema induced by inhalation of nitric oxides were investigated. The changes in the state of blood and lung antioxidant system components accompany the development of toxic pulmonary edema and coincide in time-course of edema manifestation. The determined changes were more pronounced in blood than in lungs.

摘要

研究了吸入一氧化氮所致中毒性肺水肿大鼠血液和肺中抗氧化系统的酶促和非酶促成分状态以及脂质过氧化过程。血液和肺抗氧化系统成分状态的变化伴随着中毒性肺水肿的发展,且与水肿表现的时间进程一致。所确定的变化在血液中比在肺中更为明显。

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