Pliushch S I, Zupanets I A, Drogovoz S M, Isaev S G
Eksp Klin Farmakol. 1993 Sep-Oct;56(5):53-5.
The effects of glycosamine aminosugar on the processes of endotoxicosis and lipid peroxidation were thoroughly studied in rats with toxic pulmonary edema. There was a glycosamine-induced decrease in markers of endotoxicosis, such as medium-weight molecular peptides and malonic dialdehyde in serum and lung tissue. Administration of exogenous glucosamine resulted in its incorporation into the membranes of target organs, connective tissue and normalized the levels of endogenous N-acetyl-glucosamine, which finally determined antitoxic and antioxidative properties in this aminosugar.
在患有中毒性肺水肿的大鼠中，对氨基葡萄糖氨基糖对内毒素血症和脂质过氧化过程的影响进行了深入研究。氨基葡萄糖可使内毒素血症标志物降低，如血清和肺组织中的中分子量分子肽和丙二醛。外源性氨基葡萄糖的给药导致其掺入靶器官、结缔组织的膜中，并使内源性N - 乙酰葡萄糖胺水平正常化，这最终决定了这种氨基糖的抗毒和抗氧化特性。
