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青光眼患者的角膜厚度:一个重要参数?

Corneal thickness in glaucoma: an important parameter?

作者信息

Brusini P, Miani F, Tosoni C

机构信息

Eye Unit, S: Maria della Misericordia, Udine.

出版信息

Acta Ophthalmol Scand Suppl. 2000(232):41-2. doi: 10.1111/j.1600-0420.2000.tb01097.x.

DOI:10.1111/j.1600-0420.2000.tb01097.x
PMID:11235530
Abstract

Central corneal thickness was measured by pachometry in 49 patients with primary open-angle glaucoma (POAG), 41 with ocular hypertension (OHT), 14 with normal tension glaucoma (NTG) and 48 normal subjects. The mean corneal thickness of the OHT patients was significantly greater than that of the normal control group. The NTG patients, on the other hand, had a cornea on average thinner than the normals. These differences may cause misclassification of normals with a thick cornea as ocular hypertensive eyes or, contrarywise, cause those normals whose IOP is underestimated because of a thin cornea to be classed as NTG patients.

摘要

采用角膜厚度测量仪对49例原发性开角型青光眼(POAG)患者、41例高眼压症(OHT)患者、14例正常眼压性青光眼(NTG)患者及48例正常受试者进行中央角膜厚度测量。高眼压症患者的平均角膜厚度显著大于正常对照组。另一方面,正常眼压性青光眼患者的角膜平均比正常人薄。这些差异可能导致角膜厚的正常人被误分类为高眼压眼,或者相反,导致那些因角膜薄而眼压被低估的正常人被归类为正常眼压性青光眼患者。

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引用本文的文献

1
The central corneal thickness in normal tension glaucoma, primary open angle glaucoma and ocular hypertension.正常眼压性青光眼、原发性开角型青光眼和高眼压症患者的中央角膜厚度
J Clin Diagn Res. 2013 Jun;7(6):1063-7. doi: 10.7860/JCDR/2013/4292.3022. Epub 2013 Jun 1.
2
Long axial length as risk factor for normal tension glaucoma.眼轴长度过长作为正常眼压性青光眼的危险因素。
Graefes Arch Clin Exp Ophthalmol. 2009 Jun;247(6):781-7. doi: 10.1007/s00417-009-1045-2. Epub 2009 Feb 5.
3
Microphthalmia, persistent hyperplastic hyaloid vasculature and lens anomalies following overexpression of VEGF-A188 from the alphaA-crystallin promoter.
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Mol Vis. 2007 Jan 19;13:47-56.
4
Glaucoma studies from 1996 to 1999 in peer-reviewed journals.1996年至1999年发表在同行评审期刊上的青光眼研究。
Graefes Arch Clin Exp Ophthalmol. 2005 Jul;243(7):629-36. doi: 10.1007/s00417-004-1105-6. Epub 2005 Feb 9.