Fleissig A, Jenkins V, Fallowfield L
CRC Psychosocial Oncology Group, Department of Oncology, Royal Free and University College London Medical School, 3rd Floor, Bland Sutton Institute, 48 Riding House Street, London W1P 7PL, UK.
Eur J Cancer. 2001 Feb;37(3):322-31. doi: 10.1016/s0959-8049(00)00415-9.
We report results from an intervention study to improve communication during consultations about randomised clinical trials of cancer therapy. Patients, eligible for a trial, completed questionnaires about information preferences and attitudes to trials prior to seeing their doctors, who were either shown these questionnaires (intervention) or not (control). Fifteen doctors participated and invited 265 patients to join one of 40 different randomised clinical trials. Most patients (77.4%) agreed to trial entry and this was predicted by the Patient's Attitudes to Trials questionnaire with an 80.4% accuracy. Accrual, length of consultation, doctor and patient satisfaction were not associated with the intervention. Further research to explore the potential use of written interventions to facilitate communication and accrual to randomised clinical trials is recommended.
我们报告了一项干预研究的结果，该研究旨在改善癌症治疗随机临床试验咨询过程中的沟通情况。符合试验条件的患者在看医生之前完成了关于信息偏好和对试验态度的问卷，医生要么查看这些问卷（干预组），要么不查看（对照组）。15名医生参与其中，并邀请265名患者参加40项不同随机临床试验中的一项。大多数患者（77.4%）同意参加试验，这可通过患者对试验态度问卷以80.4%的准确率进行预测。入组率、咨询时长、医生和患者满意度与干预措施无关。建议开展进一步研究，探索书面干预措施在促进沟通和随机临床试验入组方面的潜在用途。
